Risks and Considerations of Polynucleotide Treatments
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date of publication: 24/09/2025
Reading TIME: 1 min 22 sec
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Author of the post: Oblique
Polynucleotide treatments are an innovative development in regenerative medicine, designed to stimulate cell renewal, improve skin elasticity, and boost hydration. While considered safe for most patients, these injectable procedures do carry potential risks. The majority of side effects are mild and temporary, but understanding them is essential for safe and informed treatment decisions. Choosing a medically trained, experienced practitioner greatly reduces the likelihood of complications.
Common and Temporary Side Effects
Most reactions are minor, occur at the injection site, and resolve within a few hours to several days.
These may include:
- • Redness or swelling at the injection site.
- • Mild bruising from needle entry points.
- • Tenderness or slight discomfort.
- • Small, temporary bumps if the product is injected too superficially, which usually disappear as the solution is absorbed.
Rare but Serious Risks
Although uncommon, more significant complications can occur, particularly if the procedure is performed incorrectly:
- • Allergic reactions: In rare cases, the fish-derived DNA in polynucleotides may cause itching, hives, or swelling.
- • Infection: Poor hygiene during or after treatment may increase the risk of infection.
- • Granulomas: Small, firm nodules may form as part of the body’s immune response.
- • Vascular occlusion: A rare but serious complication where the product blocks a blood vessel, restricting circulation and requiring urgent medical care.
Contraindications
Polynucleotide treatments are not recommended for individuals who:
- • Are pregnant or breastfeeding.
- • Have active skin infections.
- • Have a known allergy to fish or fish-derived substances.
Key Takeaway
When performed by a skilled professional, polynucleotide treatments are generally safe and effective. Being aware of the potential risks and contraindications allows patients to make confident, well-informed choices on their journey to healthier, rejuvenated skin.
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Polynucleotides are naturally occurring molecules that help regenerate and repair the skin at a cellular level. They work by stimulating collagen production, improving skin elasticity and promoting deep hydration. Commonly used in aesthetic treatments, polynucleotides help reduce fine lines, improve skin texture and accelerate healing, making them ideal for rejuvenation, and anti-ageing therapies.
Benefits
- Post-Treatment Glow
- Boosts Skin Regeneration
- Strengthens the Skin Barrier
- Reduces Fine Lines and Wrinkles
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- Improves Elasticity and Firmness
- Increases Hydration for a Dewy Glow
Date of publication24/09/2025
